Introducción:
Ácidos orgánicos
Mecanismo de acción bactericida
como bombas de eflujo que consumen su ATP llevándola a la muerte. Gracias a la capacidad de eliminar bacterias, acompañada de la seguridad que presupone su uso para la industria alimentaria, los AO en las últimas décadas han sido empleados como un aditivo en la alimentación de animales de producción como aves y cerdos con miras en la disminución del uso de antibióticos promotores de crecimiento (19, 29). No obstante, aunque la capacidad bactericida de los AO ha sido ampliamente reportada y su uso como aditivo en la dieta de pollo de engorde en reemplazo al uso de antibióticos promotores de crecimiento es prometedor, en algunas

Ácidos orgánicos en la avicultura
El valor del hematocrito representa el porcentaje de eritrocitos en la sangre, siendo el valor normal en el pollo de engorde de 32% al día 21 y 34% para el día 42 de vida (6). En las investigaciones realizadas por Al-Saad et al. (2014) (4), Abdel-Fattahet al. (2008) (1) y Marín-Flamand et al. (2014) (23) no se evidencia efecto de la adición de ácidos orgánicos en la dieta sobre el hematocrito, el recuento de proteínas, y la hemoglobina de las aves. Por otro lado Al-Saad et al. (2014) (4), Kim et al. (2014) (18) y Wang et al. (2010) (36) manifiestan que el asociado linfoide del tracto gastrointestinal es influenciado positivamente por la modulación que ejercen los ácidos orgánicos sobre la microbiota en el tracto digestivo, al observar aumento en el recuento de las células de la línea
- Abdel-Fattah S, El-Sanhoury M, El-Mednay N, Abdel-Azeem F. Thyroid Activity, Some Blood Constituents, Organs Morphology and Performance of Broiler Chicks Fed Supplemental Organic Acids. Int. J Poult Sci 2008; 7(3): 215-222.https://10.3923/ijps.2008.215.222
- Adil S, Banday T, Bhat GA, Mir MS, Rehman M. Effect of Dietary Supplementation of Organic Acids on Performance, Intestinal Histomorphology, and Serum Biochemistry of Broiler Chicken. Vet Med Int 2010; 1–7. https://10.4061/2010/479485
- Agboola F, Omidiwura O, Odu O, Popoola IO, Iyayi EA. 2015. Effects of organic acid and probiotic on performance and gut morphology in broiler chicken. S Afr J Anim Sci 2015; 45(5): 494-501.
- Al-Saad S, Abbod M, Abo Yones A. Effects of some growth promoters on blood hematology and serum composition of broiler chickens. International Journal of Agricultural Research 2014, 9(5), 265–270. https://10.3923/ijar.2014.265.270
-
Apajalahti J, Kettunen A. Microbes of the chicken gastrointestinal tract. In Avian Gut Function in Health and Disease. Wallingford:CABI. 2006
-
Cardoso ALSP & Tessari ENC. Estudo dos parâmetros hematológicos em frangos de corte. Arq Inst Biol 2003; 70(4): 419–424.
-
Castanon JIR. History of the Use of Antibiotic as Growth Promoters in European Poultry Feeds. Poult 2007; 86(11): 2466–2471.https://doi.org/10.3382/ps.2007-00249
-
Cherrington C, Hinton M, Mead GC, Chopra I. Organic acids: chemistry, antibacterial activity and practical applications. Adv Microb Physiol 1991; 32(1): 87–108. https://doi.org/10.1016/S0065-2911(08)60006-5
-
Chotikatum S, Kramomthong I, Angkanaporn K. Effects of medium chain fatty acids, organic acids and fructo-oligosaccharide on cecal Salmonella enteritidis colonization and intestinal parameters of broilers. Thai J Vet Med 2009; 39(3): 245–258.
-
Davidson PM, & Taylor TM. Chemical preservatives and natural antimicrobial compounds. Food Microbiology, Fundamentals and Frontiers. Third edition Washington, D.C. 2007.
-
Dibner JJ & Buttin P. Use of Organic Acids as a Model to Study the Impact of Gut Microflora on Nutrition and Metabolism. J Appl Poult Res 2002; 11: 453–463. https://doi.org/10.1093/japr/11.4.453
-
Esmaeilipour O, Shivazad, M, Moravej H, Aminzadeh S, Rezaian M, van Krimpen MM. Effects of xylanase and citric acid on the performance, nutrient retention, and characteristics of gastrointestinal tract of broilers fed low-phosphorus wheat-based diets. Poult Sci 2011; 90(9):1975–1982. https://doi.org/10.3382/ps.2010-01264
-
Gadde U, Kim WH, Oh ST, & Lillehoj HS. Alternatives to antibiotics for maximizing growth performance and feed efficiency in poultry: a review. Anim Health Res Rev 2017; (May): 1–20. https://doi.org/10.1017/S1466252316000207
-
Gaggìa FMP. Probiotics and prebiotics in animal feeding for safe food production. J Food Microbiol 2010; 31: S15-28. https://doi.org/10.1016/j.ijfoodmicro.2010.02.031
-
Hassan HMA, Mohamed MA, Youssef AW, & Hassan ER. Effect of using organic acids to substitute antibiotic growth promoters on performance and intestinal microflora of broilers. Asian-Aust J Anim Sci 2011; 23(10): 1348–1353. https://doi.org/10.5713/ajas.2010.10085
-
Hernández F, García V, Madrid J, Orengo J, Catalá P, & Megías MD. Effect of formic acid on performance, digestibility, intestinal histomorphology and plasma metabolite levels of broiler chickens. Br Poult Sci 2006; 47(1):50–56. https://doi. org/10.1080/00071660500475574
-
Islam M, Khandaker Z, Chowdhury S, & Islam K. Effect of citric acid and acetic acid on the performance of broilers. J Bangladesh Agril Uni, 2010; 6(2): 315–320.
-
Kim DW, Kim JH, Kang HK, Akter N, Kim MJ, Na JC, Salim HM. Dietary supplementation of phenyllactic acid on growth performance , immune response , cecal microbial population , and meat quality attributes of broiler chickens. J. Appl. Poult 2014; 23: 661–670. https://doi.org/10.3382/japr.2014-00974
-
Kim JW, Kim JH, Kil, DY. Dietary organic acids for broiler chickens: a review. Revista Colombiana de Ciencias Pecuarias. Rev Colom Cienc Pecua 2015; 28(2): 109–123.
-
Kliseviciute V. Effects of dietary inclusion of medium chain fatty acids and butyrate on growth performance, organ weights, and intestinal histomorphology of broiler chickens. European sympsium on poultry nutrition 2015.
-
Kum S, Eren U, Onol A, Sandikci M. Effects of dietary organic acid supplementation on the intestinal mucosa in broilers. Rev. Med. Vet 2010; 161(10): 463–468.
-
Mani-López E, García HS, & López-Malo A. Organic acids as antimicrobials to control Salmonella in meat and poultry products. Food Res Int 2012; 45(2):713–721. https://doi.org/10.1016/j.foodres.2011.04.043
-
Marín-Flamand E, Vázquez-durán A, & Méndez-albores A. Effect of Organic Acid Blends in Drinking Water on Growth Performance, Blood Constituents and Immune Response of Broiler Chickens. J Poult Sci 2014; 51(2): 44-50. https://doi.org/10.2141/ jpsa.0120179
-
Nourmohammadi R, Khosravinia H, Afzali N, & Manafi M. Effects on productive performance, tibia calcium and phosphorous retention, and liver enzymes activity of acidified and alkalinized diets in broiler chicken. Ann Anim Sci 2016: 1–23. https://doi.org/10.1515/aoas-2016-0001
-
Panda AK, Rao SVR, Raju MVLN, & Sunder GS. Effect of butyric acid on performance, gastrointestinal tract health and carcass characteristics in broiler chickens. Asian-Australas J Anim Sci 2009; 22(7): 1026–1031. https://doi.org/10.5713/ajas.2009.80298
-
Paul SK, Halder G, Mondal MK & Samanta G. Effect of organic acid salt on the performance and gut health of broiler chicken. J Poult Sci 2007; 44: 389–395. https://doi.org/10.2141/jpsa.44.389
-
Pelicano E, Souza P, Souza H, Figueiredo D, Boiago M, Carvalho S & Bordon V. Intestinal mucosa development in broiler chickens fed natural growth promoters. Rev Bras Cienc Avic 2005; 7(4): 221–229. http://dx.doi.org/10.1590/S1516-635X2005000400005
-
Pirgozliev V, Murphy TC, Owens B, George J & McCann MEE. Fumaric and sorbic acid as additives in broiler feed. Res Vet Sci 2008; 84(3): 387–394.https://doi.org/10.1016/j.rvsc.2007.06.010
-
Ricke SC. Perspectives on the use of organic acids and short chain fatty acids as antimicrobials. Poult Sci 2003; 82(4): 632–639. https://doi.org/10.1093/ps/82.4.632
-
Rinttilä T. & Apajalahti J. Intestinal microbiota and metabolites — Implications for broiler chicken health and performance. J. Appl. Poult Res 2013; 22: 647–658. https://doi.org/10.3382/japr.2013-00742
-
Salanitro JP, Blake IG, Muirhead PA. Studies on the cecal microflora of commercial broiler chickens. Appl Microbiol 1974; 28(3):439 47
-
Świątkiewicz S & Arczewska-Wlosek A. Bone quality characteristics and performance in broiler chickens fed diets supplemented with organic acids. Czech J Anim Sci 2012; 57(4): 193–205. https://10.3923/ajpsaj.2010.7.11
-
Talebi E, Zarei A & Abolfathi M. Influence of three Different Organic Acids on Broiler Perfonrmance. Asian J Poult Sci 2010; 4(1): 7-11.
-
Uni Z, Ganot S, & Sklan D. Posthatch development of mucosal function in the broiler small intestine. Poult Sci 1998; 77(1): 75–82. https://doi.org/10.1093/ps/77.1.75
-
Vieira SL, Oyarzabal OA, Freitas DM, Berres J, Peña JEM, Torres CA, & Coneglian JLB. Performance of broilers fed diets supplemented with sanguinarine-like alkaloids and organic acids. Journal of Appl Poult Res 2008; 17(1): 128–133. https://doi.org/10.3382/japr.2007-00054
-
Wang JP, Lee JH, Yoo JS, Cho JH, Kim HJ, & Kim IH. Effects of phenyllactic acid on growth performance, intestinal microbiota, relative organ weight, blood characteristics, and meat quality of broiler chicks. Poult Sci 2010; 89(7): 1549–1555. https://doi. org/10.3382/ps.2009-00235



Artículo original: Ángel-Isaza J, Mesa-Salgado N, Narváez-Solarte W. Ácidos orgánicos, una alternativa en la nutrición avícola: una revisión. Rev. CES MEDICINA VETERINARIA Y ZOOTECNIA; 2019; Vol 14 (2): 45-58. http://dx.doi.org/10.21615/ cesmvz.14.2.4 ISSN 1900-9607
Autor de la publicación
Jaime Ángel-Isaza; Natalia Mesa-Salgado; William Narváez-Solartejaime.angel92@gmail.com